106: Review of Screening Program Effect on Incidence of Hemolytic Disease Due to G6pd Deficiencies
نویسندگان
چکیده
Background and aims: G6PD deficiencies is a genetically issue that is noticed and is wide spread in our region and around the world. Despite the screening program for this disease since 2005 there are noticeable cases. Methods: In this descriptive study the file of 923 patients that were diagnosed with Favism and hospitalized in Khorramabad hospitals during 2005 and 2015 were reviewed. This information includes the number of occurrence for each year, the causes of new cases which analyzed and recorded. Conclusion: Even so the cases reduced from 102 at 2005 to 33 at 2015 (60% reduction) but the most case were on 2009 and 2013 with 102 case and 145 case respectively. The cause of developing of these case is under observation and consideration. The most noticeable causes of occurrences are misunderstanding of the parents from permanent nature of disease (63.0%), neglecting disease (12.0%), Lack of providing of screening results to parents (12.0%) and use of Oxidant agents without parental supervision (8.0%), use of wrong Oxidant medication (5.0%).Despite of large expenses for screening program it seems that educate and providing information to the parents needs revision.
منابع مشابه
Prevalence of G6PD deficiency in neonates referred to Semnan University of Medical Science´s screening Lab
Abstract Background and objectives: Glucose-6-phosphate dehydrogenase (G6PD) is an enzyme in the pentose phosphate pathway. G6PD deficiency (an X-linked recessive hereditary disease) is an inherited condition affecting approximately 3% of the people globally. This deficiency can cause hemolytic anemia and jaundice in neonates. The goal of this study is to detect the prevalence of G6PD deficienc...
متن کاملRed cell enzymes.
Mutations leading to red cell enzyme deficiencies can be associated with diverse phenotypes that range from hemolytic anemia, methemoglobinemia, polycythemia, and neurological and developmental abnormalities. While most of these mutations occur sporadically, some such as common glucose-6-phosphate dehydrogenase (G6PD) mutants are endemic and rarely cause disease. Common G6PD mutants likely reac...
متن کاملCLINICAL PRESENTATION OF GLUCOSE-6- PHOSPHATE DEHYDROGENA SE (G6PD) DEFICIENCY: A PILOT STUDY
Sixty-six children with G6PD deficiency were evaluated retrospectively to ascertain the clinical features, etiology, ultimate outcome and population at risk, The occurrence of jaundice in 18 neonates (group J) was, contrary to other countries, in the form of neonatal jaundice type II. Sepsis, prematurity, hypoxia and acidosis were associating factors. 77.8% of neonates had exchange blood t...
متن کاملNewborn screening for Glucose-6-Phosphate Dehydrogenase Deficiency in Eastern Province, Saudi Arabia
Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency is an x-linked recessive disorder expressed mostly in males. Patients with G6PD deficiency may present clinically with evidence of hemolytic anemia in the neonatal period or later in life, or may remain asymptomatic. The aim of this study was to determine the incidence of G6PD deficiency in Saudi infants screened at birth. All Saudi infants bo...
متن کاملEpidemiologic Study of G6PD deficiency in infants with Jaundice in Khalij-Fars Hospital of Bandar-Abbas in 2015
Background: The purpose of this study was to determine the prevalence of G6PD deficiency in infants with jaundice in Khalij-Fars Hospital of Bandar Abbas in 2015. Methods: In this descriptive-analytic cross-sectional study, which is done in 2015 in Khalij-Fars Hospital of Bandar-Abbas, 226 infants with jaundice were entered. Admission age, hospitalization time, gender, age of birth, birth weig...
متن کامل